ZFIN Image: Fang et al., 2025, Figure 5

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Figure 5

Pyripyropene O inhibits the growth of xenograft prostate cancer PC-3 cells in zebrafish. (a) Procedure for establishing a zebrafish xenograft tumor model. (b) Distribution of prostate cancer PC-3 cells before administration of Pyripyropene O in zebrafish xenografts. (c) Distribution of prostate cancer PC-3 cells in zebrafish after 72 h treatment with different concentrations of Pyripyropene O. (d) Intensity of fluorescence in zebrafish in each group before drug administration. (e) Fluorescence intensity in zebrafish from each group after 72 h of PyrO treatment. (f) Zebrafish survival rate after Pyripyropene O administration. * p < 0.05, ** p < 0.01 vs. vehicle.

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