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Fig. 7 Panx2 ablation impairs the optomotor response of larvae. OMR was used to assess optic flow processing in 6 dpf Panx2+/+ and Panx2Δ11 larvae, at two light intensities (10 % and 100 %). Both groups were shown visual stimulus of moving stripes at three spatial frequencies (64, 128, and 256), which were presented at 72 pixels/s and 144 pixels/s. The line graphs show the percentage of larvae that indicated the expected positive response, from n = 16 for each genotype. Panx2Δ11 larvae had significantly lower visual acuity when compared to Panx2+/+. ***P-value<0.001, **P-value<0.01, *P-value<0.05, ns = not a significant difference. See also Supplementary Table 6.
Reprinted from Biochimica et biophysica acta. Molecular basis of disease, , Shanbhag, R., Zoidl, G.S.O., Nakhuda, F., Sabour, S., Nauman, H., Zoidl, C., Bahl, A., Tabatabaei, N., Zoidl, G.R., Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish, 167807167807, Copyright (2025) with permission from Elsevier. Full text @ BBA Molecular Basis of Disease