ZFIN Image: Wu et al., 2025, Fig. 4

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Figure Caption

Fig. 4

Effect of FECH overexpression on invasion and proliferation in KDM4C-knockdown SAS and FaDu cells. A, B Analysis of FECH expression in LKO and KDM4C-knockdown (shKDM4C#1 or #2) SAS (A) and FaDu (B) cells. Cells were transfected with control or Flag-FECH expression vector, followed by Western blot analysis. C, D Invasion assay of LKO and FECH-overexpressing KDM4C-KD SAS (C) and FaDu (D) cells. E, F MTT cell proliferation assay of LKO and FECH-overexpressing KDM4C-KD SAS (E) and FaDu (F) cells at indicated time points. Data in (C, D) are represented in individual points and mean, and data in (E, F) are mean ± SD. P-values are determined by one-way ANOVA with Tukey’s multiple comparisons test (C, D) and two-way ANOVA with Tukey’s multiple comparisons test (E, F). *P < 0.05, **P < 0.01, ***P < 0.001, ns not significant

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