Fig. 1 OTA inhibits proliferation and cell viability and induces cell cycle arrest in LO2 cells (A) Chemical structures of ochratoxin A. Viability assay via automatic cell counting: (B) Represented images, the green cells indicated live cells while the red cells indicated dead cells (n = 3); (C) Number (left) and ratio (right) of live cells at indicated concentrations (n = 3). (D) Changes in cell viability of LO2 cells after 48 h of incubation with OTA at indicated concentrations (n = 6). (E) Flow cytometry analysis of cell cycle distribution following 48 h of OTA treatment (n = 3). Data were presented as mean ± S.D. *p < 0.05, * *p < 0.01, * **p < 0.001, * ** *p < 0.0001 vs. vehicle group.
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