Assessment of ROS levels, MSC viability, and the effect of homotaurine treatment during a 14-day period. (A) A significant increase in reactive oxygen species (ROS) levels was observed starting from day 3, suggesting a correlation between elevated ROS and cellular aging in mesenchymal stem cells (MSCs). (B) No significant differences in cell viability were noted after 3 days of culture, while a marked improvement in cell viability was observed on day 14. (C) This cell viability increase was associated with a reduction in ROS levels following homotaurine treatment, also on day 14, with no previous alteration after 3 days of treatment. (* p < 0.05; ** p < 0.01; *** p < 0.005).
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Full text @ Antioxidants (Basel)
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