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Fig. 7 The c-mybhyper;pu.1G242D/G242D MDS/sAML model responds to the combination of all-trans retinoic acid and cytarabine treatment. (A) Flowchart for drug treatment in wt, c-mybhyper, pu.1G242D/G242D, and c-mybhyper;pu.1G242D/G242D embryos. (B) The combination treatment of Ara-C and ATRA decreased the number of neutrophils in the CHT region as determined by SB staining. (C) Average numbers of SB+ cells per embryo with drug treatment at 5 dpf (n ? 12).
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