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Figure 4
High-frequency rRNA variants detected in humans. (A) 80S human ribosome with modeled expansion segments labelled at high-frequency allelic variant positions (>20%). (B) 40S small subunit of human ribosome with high-frequency variant alleles. (C) 60S large subunit of human ribosome with variant high-frequency variant alleles. Key structural features of the ribosome are indicated. Key: rRNA, tan; RP, green; variant nucleotide, red; posttranscriptional modifications, purple. Model based on PDB: 8G5Y. Gray labels of expansion segments indicate their relative distance from the viewers perspective.
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Full text @ Phil. Trans. Roy. Soc. Lond., Series B