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Fig. 2 Comparison of IC50 values of pharmaceuticals between human and zebrafish GPCRs plots indicate the ratio of IC50 values of pharmaceuticals against human and zebrafish GPCRs. Ratio > 1 indicates that zebrafish GPCRs were more strongly inhibited by pharmaceuticals; <1 indicates that human GPCRs were more strongly inhibited by pharmaceuticals. Red open circle indicates that the ratio was below 0.01 because the IC50 of atenolol against zβ1 receptor was not detected in the tested concentration range.
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