Fig. 2

Fig. 2

SNHG4 promoted the proliferation and migration of glioma cells in vitro. a The knockdown efficiency of SNHG4 was detected in Ln229 cells by qRT-PCR assay when transfection with si1-SNHG4, si2-SNHG4 and NC (P = 0.0027 and 0.0002). b The knockdown efficiency of SNHG4 was detected in U251 cells by qRT-PCR assay when transfection with si1-SNHG4, si2-SNHG4 and NC (P = 0.0030 and 0.0011). c. The overexpression efficiency of SNHG4 was detected in U87 cells by qRT-PCR assay when transfection with pcDNA3.1-SNHG4 plasmids (P = 0.0492). d, e CCK-8 assay were used to assess the proliferation of Ln229 (D) and U251 (E) cells after knocking-down SNHG4. f For overexpression of SNHG4 in U87 cells, the CCK-8 assay was used to assess the cell proliferation. g, h Transwell assays were performed to examine cell migration in Ln229 (g) and U251 (h) cells transfected with SNHG4 siRNAs (P = 0.0156 and 0.0064, P = 0.0067 and 0.0101). i. Transwell assays were performed to examine cell migration in U87 cells when transfection with pcDNA3.1-SNHG4 plasmids. *: P < 0.05, **: P < 0.01, ***: P < 0.001