ZFIN Image: Carrara et al., 2025, Fig. 7

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Figure Caption

Fig. 7

Inactivation of MMEJ sensitizes zebrafish embryos to IR. Embryos at 4 hpf were exposed to ionizing radiation (0, 2 and 6 Gy) and allowed to develop until 24 hpf. Phenotype was scored at 24 hpf according to the right panel scale. Weak = minor deformation of the tail, Mild = major deformation of the tail, Strong = atrophied tail and head, dead embryos were not imaged. WT, n = 140; MZlig3, n = 59; MZpolq, n = 71; and lig4, n = 22. P-values from Fisher’s Exact Test are indicated. Results for each mutant genotype at each dose were compared to those of wild-type samples at the corresponding dose. Image scale bar: 500 microns.

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