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Fig. 4 L3T mRNA vaccine induces DNA damage repair (A) Heatmap of differentially expressed genes (DEGs) of zebrafish immunized with L3T or the LPP control. (B) Enrichment of upregulated genes in the L3T immunized zebrafish by GO analysis. (C) DNA break repair pathways. Genes upregulated in the L3T immunized zebrafish were highlighted in red. (D and E) GSEA of the DEGs in L3T immunized groups compared with the control LPP group.
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