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Fig. 4 Comparative analysis of gene expression patterns in runx2b+/+ and runx2b−/− zebrafish. A–C Intersection genes between 69 specific genes in IB-containing fish (Fig. 3E left) and genome editing zebrafish DEGs (differential expressed genes). Expression patterns of intersecting genes in different groups. D–F Intersection genes between 79 differentially expressed genes conserved across species (Fig. 3E right) and genome editing zebrafish DEGs. Expression patterns of intersecting genes in different groups. G–I Intersection genes between 91 IB-specific expression genes by tau and genome editing zebrafish DEGs. Expression patterns of intersecting genes in different groups. Cid, grass carp; Mam, blunt snout bream; Ipu, channel catfish; Tfu, yellow catfish