Fig. 6

Fig. 6

Cytoscape visualization of the main clusters of the final molecular network of fraction 06104_D (TOP) and 03283_B (BOTTOM), for each GNPS analysis approach. Compound families’ identifications were done using ClassyFire¹⁸. In the classic GNPS approach, larger nodes are masses that are unique to the bioactive fraction, whereas in the bioactivity-based molecular network approach, the size of the nodes is proportional to their significance to the observed bioactivity. Each color represents a fraction with the same solvent polarity from cyanobacteria strains belonging to the genus Nodosilinea. The dark blue color corresponds to the positive hits, fractions 06104_D and 03283_B, respectively, while the others are from non-active fractions. Networks derived from Cytoscape 3.10.0 23¹⁹.