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Fig. 4 MTT assay for cytotoxicity of coumestrol. Neuronal cell lines (N2A and SH-SY5Y) and kidney cell lines (COS-7 and HEK-293) were treated with coumestrol. All results are presented as the mean ± SEM (n = 3). Statistical significance was determined by Kruskal-Wallis test followed by Dunn's post-hoc test (* p < 0.05, ** p < 0.01, *** p < 0.005).
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Reprinted from International journal of biological macromolecules, 282(Pt 4), Peng, C.H., Hwang, T.L., Hung, S.C., Tu, H.J., Tseng, Y.T., Lin, T.E., Lee, C.C., Tseng, Y.C., Ko, C.Y., Yen, S.C., Hsu, K.C., Pan, S.L., HuangFu, W.C., Identification, biological evaluation, and crystallographic analysis of coumestrol as a novel dual-specificity tyrosine-phosphorylation-regulated kinase 1A inhibitor, 136860, Copyright (2024) with permission from Elsevier. Full text @ Int. J. Biol. Macromol.