ZFIN Image: Ramakrishnan et al., 2025, Fig. S1

Image

Figure Caption

Fig. S1 Macrophages accumulate and extend protrusions into the tumor mass correlated with tumor invasion. (A) Representative stills from time-lapse imaging of ZMel1 transplanted larvae from 1 to 6 hpi. (B) Quantification of neutrophils and macrophages every hour from 1 to 6 hpi indicated by average values at each time point. n = 4 larvae. (C) Representative z-projected stills from LSM imaging of tumor-macrophage interactions at 48 hpi imaged every minute. Lines indicate macrophage protrusions and invading tumor cells (n = 4). (D) Quantification of protrusion length of macrophages when in contact with invading tumor versus not in contact from light sheet microscopy (n = 3, from two independent experiments).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Biol.