ZFIN Image: Smith et al., 2024, Fig. 5

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Figure Caption

Fig. 5

Dual FGFR/VEGFR inhibition with Lenvatinib induces tumor stasis or regression in all AM PDX tumors. Tumor growth velocity for individual Sunitinib (daily, 40 mg/kg) and Lenvatinib (daily, 50 mg/kg) treated PDX tumors are represented as violin plots (A, C). The Lenvatinib-treated tumors from (A, C) are shown as bar plots that are color-coded based on depth of response (B, D). CM tumors are indicated by a checkerboard pattern. Average tumor growth of vehicle and Lenvatinib treated CM (E) and AM (F) are shown for all of the tested PDX models. Two-way ANOVA was used to determine differences between CM and AM therapy response (B-D), and student T-tests were used to compare vehicle and treatment differences within a PDX model (A, C, E–F)

Acknowledgments

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