ZFIN Image: Roux et al., 2024, Figure 6.

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Figure Caption

Figure 6.

Single-cell analysis reveals inhibition of cytoplasmic translation and enhanced phagocytosis in HuNoV-infected macrophages. (a) A volcano plot shows the DEGs in HuNoV-infected vs. uninfected bystander macrophages within the HuNoV-infected zebrafish host. A vertical dotted line marks a log₂(fold change) value of 0.5, while the horizontal dotted line marks a benjamini-Hochberg q-value of 0.05. Dot plot showing the pathways obtained via a ClueGO hypergeometric enrichment pathway analysis of (b) downregulated and (c) upregulated DEGs using the gene ontology - biological process database. HuNoV = human norovirus, DEGs = differentially expressed genes.

Acknowledgments

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