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Fig. 4

ID: ZDB-IMAGE-241031-14
Publication: Baird et al., 2024 - Rare homozygous cilia gene variants identified in consanguineous congenital heart disease patients
All Figures: Figures for Baird et al., 2024

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Figure Caption

Fig. 4

Temporal localization of ADCY6 to primary cilia during cardiomyogenesis. ADCY6 accumulate at primary cilia during differentiation of P19.CL6 cells into cardiomyocytes. a Representative images P19.CL6 cells at day 0 (stem cells) and day 10 (cardiomyocytes). Arrows point to primary cilia. Scale bar, 10 µm. b 3D visualization of representative cilia at day 0 and day 10 of differentiation. Arrow points to the primary cilium. Asterisk marks the ciliary base. c Violin plots of quantification of ADCY6 fluorescence levels at primary cilia during days 0, 7, 10 and 12 of differentiation. Asterisks indicate P values: ****P < 0.0001

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