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Fig. 8
Identifying changes in heart rate in zebrafish following treatment with SPN that either decrease or enhance heart contraction rate. The heart rate of 10 zebrafish was monitored right before administering the medication (A). Note that the same response to drug administration was observed in all zebrafish Statistical analysis of zebrafish indicates that SPN regulates cardiac rate after expressing electrical stimulation (B). The experiments were expressed as mean ± SD. Three independent biological replicates were included. ∗p < 0.05, compared among groups.
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