IMAGE

Fig. 3

ID: ZDB-IMAGE-240930-119
Publication: Shojaeinia et al., 2024 - Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons
All Figures: Figures for Shojaeinia et al., 2024

Image

Figure Caption

Fig. 3

Partial rescue of dhps knockdown larvae by expression of dhps mRNA at 1 day post-fertilization (1 dpf). (A) Map of pIVT construct with zebrafish dhps cDNA. (B) mRNA overexpression partially shifted the more severe phenotypic categories of dhps knockdown to less severe categories. Chi-square analysis showed significant differences between control, knockdown and rescue groups with regard to the percentages of embryos exhibiting normal development, mild and moderate dysmorphology (P<0.0001). (C) Definition of observed phenotypic categories and sample size of each group

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Brain