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Figure 6

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ZDB-IMAGE-240823-33
Publication
Grepper et al., 2024 - BCL2L13 at endoplasmic reticulum-mitochondria contact sites regulates calcium homeostasis to maintain skeletal muscle function
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Figures for Grepper et al., 2024
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Figure Caption

Figure 6

Ca2+ dynamics in siBCL2L13 and siControl C2C12 myotubes

(A) 300 s confocal time-lapse recording of cytosolic Ca2+ levels.

(B) Quantification of normalized Fluo-4 fluorescence in response to 2.5 mM caffeine.

(C) 300 s confocal time-lapse recording of mitochondrial Ca2+ levels.

(D) Normalized Rhod-2 fluorescence in response to 1 μM thapsigargin. (A–D) n = 4 independent transfections per condition. (B and D) peak fluorescence was normalized to baseline. Error bars are mean ± SEM, ∗p < 0.05, ∗∗p < 0.01, ∗∗∗∗p < 0.0001 (unpaired t test).

See also Figure S5.

Acknowledgments
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