ZFIN Image: Gawel et al., 2024, Figure 4

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Figure 4

Spontaneous local field potentials (LFPs) recorded from the brain of zebrafish larvae previously exposed to pilocarpine (PILO). Larvae were incubated in medium containing PILO (50 mM) for 120 min, and, afterwards, larvae were thoroughly washed out 5 times in fresh medium and incubated in PILO-free medium for the next 22 h. Subsequently, LFP recordings were performed: (A–E) representative pattern of electrographic events recorded 22 h after acute exposure to PILO (50 mM). Note unprovoked, recurrent abrupt seizure-like events with miscellaneous patterns, duration and amplitude.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.