Fig. 3 Treatment with BMS partially rescues the heart phenotype in cxcr4a−/− embryos (A) Experimental designing for BMS treatment and the subsequent experiments. (B) Expression of myl7 in wild-type embryos, cxcr4a−/− embryos and cxcr4a−/− embryos treated with BMS (0.04 μM) from 4hpf to 20hpf. The dowregulation of myl7 expression in cxcr4a mutants is restored after treating with BMS. (C) The area of myl7 expression is increased in cxcr4a mutants after treating with BMS. (D) BMS treatment partially rescues pericardial effusion and erythrocyte remaining in cxcr4a mutants (Dd10-Dd12, black arrow head showed). Error bars indicate standard deviation of the mean. Bar, 50 μm *P<0.05.
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