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Fig. 18 Schematic summary of two-pore domain potassium (k2p) gene expression in 48 h postfertilization (hpf) zebrafish embryos. (A) The zebrafish k2p gene expression is summarized for their expression in major organs or tissues. (B) The summary of zebrafish k2p genes that were detected in the brain. The forebrain, midbrain, and hindbrain are color-coded. The anatomic structures are made according to the atlas of embryonic zebrafish brain.51 Hyp, hypothalamus; MHB, midbrain–hindbrain boundary; OB, olfactory bulb, ORR, optic recess region; p, pallium; s, subpallium; TALK, TWIK-related alkaline pH-activated K+; TASK, TWIK-related acid-sensitive K+; Teg, tegmentum; THIK, tandem pore domain halothane-inhibited K+; TREK, TWIK-related K+; TRESK, TWIK-related spinal cord K+; TWIK, tandem of pore domains in a weak inward rectifying K+.