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Fig. 2 Changes in cell viability upon exposure to the derivatives in Hep3B and SkHep1 cells. (A) Known and novel derivatives’ IC50 values; (B) PCA on cell viabilities across different doses of drugs; and (C) side-chain modifications by the intermediary and novel derivatives and their influences on the IC50 levels. Significance levels (p-values) are derived from n-way ANOVA for each respective comparison in R environment.
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