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Figure Caption
Fig. 4 Progression of hepatocarcinogenesis induced by Dox in krasV12 zebrafish after MC-LR exposure. (A)– (E): Representative liver morphology pictures of krasV12 zebrafish. Scale bar, 2 mm (A/a: control; B/b: Dox; C/c: Dox + MC-LR (0.1 μg/L); D/d: Dox + MC-LR (1 μg/L); E/e: MC-LR (1 μg/L). Evidence of HCC (lost hepatocyte plates, large and variable nuclear size, and presence of multiple nucleoli) is indicated by the black arrows. Scale bar, 50 µm. (F) and (G): Effects of MC-LR on HSI values and mean gray values in krasV12 zebrafish liver (n = 8). Values are mean ± S.E.
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