ZFIN Image: Fabian et al., 2024, Figure 4

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Figure Caption

Figure 4

Swimming behaviour is defective in neb mutants. Muscle performance and function in neb mutants was assessed by tracking optovin-induced swimming of embryos at 7 dpf. Graphs showing time spent moving, distance travelled, and speed for each zebrafish line. The nonsense mutants neb¹⁵ and neb¹¹ showed significantly shorter time swimming, distance travelled, and lower speed compared to their siblings. The splice mutants neb³⁴ and neb²¹, with mutations in SR region, also showed significantly shorter time spent swimming. The motor behaviour of the splice mutant neb³⁰ is not significantly different from that recorded for its siblings. Graphs display values normalized to wt (mean ± SEM). Asterisks indicate p-values (* ≤ 0.05; ** ≤ 0.01; *** ≤ 0.001; **** ≤ 0.0001). See Supplemental Table 3 for descriptive statistics.

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Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.