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Fig 2 Overt disease observed in laboratory zebrafish cohoused with zebrafish from the pet trade is associated with RMBV infection.
(A) Diagram of cohousing experiment. Tanks were seeded with adult zebrafish from the laboratory (control) or zebrafish from the laboratory and the pet trade (cohoused). (B) A representative individual from the control tank. (C) A representative laboratory zebrafish 1 month after cohousing with zebrafish from the pet trade. Red arrows highlight necrotic lesions. (D) Transmission of microbes from pet trade to cohoused laboratory zebrafish inferred from host and microbe transcript abundances. Three laboratory fish were sampled from each tank. Samples are grouped by tank and tissue. Columns show estimated transcript abundances in tissue samples from individual laboratory zebrafish. RMBV, Rocky Mountain birnavirus.