ZFIN Image: Hernández-Urcera et al., 2024, Figure 4

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Figure Caption

Figure 4

In vivo evaluation of the anti-inflammatory activity of the extracts (at 25 μg mL⁻¹) using zebrafish larvae. The different algal groups selected are indicated. (A) The transgenic zebrafish larvae Tg(lyz:DsRed2) was used. The lysozyme-expressing cells (neutrophils) are marked in red and can be analyzed in live animals. Scale bar = 500 µm; (B) Control animals were injured in the tail and the number of neutrophils was measured at 2 h, 24 h and 48 h. Scale bar = 100 µm; (C) Evolution in the number of neutrophils at the injury in control fish. The graph was created using information obtained from 50 animals. (D) Effect of the extracts on the number of neutrophils at the injured fin. Results represent the mean and SD. (*) asterisks represent significant differences (p < 0.05) compared to controls.

Acknowledgments

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