Figure 1

Figure 1

Amino acid sequence and structure of Crotoxin B (PLA₂) from Crotalus durissus terrificus snake venom. (A) Amino acid sequence of Crotoxin B. The regions that originated the peptides 1, 2, and 3 are shown within the blue, orange, and red boxes, respectively. The residues from the catalytic site are highlighted in yellow, while the residues from the Ca²⁺ binding site are highlighted in green. The residues highlighted in purple are important for Crotoxin B toxicity/lethality, myotoxicity, edema induction, antibacterial, liposome-disrupting, enzymatic, and anticoagulant activities. (B) Structure of Crotoxin B (PDB: 2QOG) with the regions that originated peptides 1 and 2 highlighted with carbon atoms in green and peptide 3 highlighted with carbon atoms in purple.