FIGURE 2

FIGURE 2

The electrocardiogram profile of bigheart fish indicates signs of arrhythmia. (A) Electrocardiogram recordings of wild-type (bh^+/+) zebrafish. X-axis represents time in milliseconds (ms), and Y-axis represents voltage in millivolts (mV). (B) Electrocardiogram recording of bh^−/− fish, red arrowhead represents the absence of beats. (C) Graph representing the R-R interval in wild type and bh^−/− fish. (D) Graph representing heart beat rate in adult wild type (bh^+/+) zebrafish and bh^−/− fish. (E) Graph showing an overlay of wild type and bh^−/− mutant ECG recordings (Regular line and dashed line represents the ECG profiles of wild type and bh^−/− fish, respectively). P, Q, R, S and T represent regular ECG waves. (**, p < 0.01). The bars indicate the average values ± SD.