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Fig. 1 Effects of HXP on the phenotype and cardiac function of zebrafish embryos A. Zebrafish embryos at 48 hpf were exposed to various doses of HXP (0–640 μg/mL) for 4 h. The phenotypes were classified as normal, moderate and severe, scale bar = 200 μm. B. Statistics of phenotypic proportions of zebrafish embryos exposed to different doses of HXP (0–640 μg/mL) for 4 h, n = 30, the experiment was replicated three times. C. Statistics of the heart rate of zebrafish embryos exposed to different doses of HXP (0–320 μg/mL) for 4 h, n = 30, compared with those of the 0 μg/mL treated group. D. Statistics of heart fractional shortening of zebrafish embryos exposed to different doses of HXP (0–160 μg/mL) for 4 h, n = 10, compared with those of the 0 μg/mL treated group (DMSO group).