ZFIN Image: Camacho-Macorra et al., 2024, FIGURE 7

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Figure Caption

FIGURE 7

Proposed model for maternal vgll4a contribution to zebrafish epiboly progression. Maternal vgll4a promotes plasma membrane localization of the E-cadherin/β-catenin complex in the amount required for an adequate cohesion among blastomeres. This cohesion threshold allows tissue mechano-sensing and thus yap1-dependent mechano-transduction. Signal transduction impacts on the organization and function of the actomyosin ring, thereby promoting timely epiboly progression. E-cad, E-cadherin; β-cat, β-catenin; F-act, F-actin.

Acknowledgments

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