ZFIN Image: Wen et al., 2024, Figure 7

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Figure Caption

Figure 7

The antioxidative activity of SA depends on NRF2 in Mm-infected macrophages. (A–C) Western blotting analysis of the effects of 0.5 mM SA on the protein expression of HO-1 and NQO-1 in Mm-infected macrophages isolated from WT and NRF2^−/− mice (n = 3). (D–G) Western blotting analysis of the effects of 0.5 mM SA on the AMPK-α1, GSK-3β, and AKT signaling pathway in Mm-infected macrophages isolated from WT and NRF2^−/− mice (n = 3). (H,I) The levels of GSH and MDA in Mm-infected macrophages isolated from WT mice (n = 3). (J,K) The levels of GSH and MDA in Mm-infected macrophages isolated from NRF2^−/− mice (n = 3). Means ± SEM; no significance, ns; * p < 0.05, ** p < 0.01, and *** p < 0.001.

Acknowledgments

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