Fig 4

Fig 4 The relationship between DE genes and DAR along the entirety of mouse Chromosome 7 between male APOE2/2 and APOE3/3 mouse cerebral cortices (at 3 months of age).

The plot contains four sets of information represented by separate tracks horizontally. Track A represents the axis of Chromosome 7. The position of the APOE gene is marked and labelled in bold red. Track B displays differentially expressed genes according to their positions along the chromosome. 99 of 1126 total genes (8.79%) on Chromosome 7 that were expressed in the dataset were classified as DE (FDR < 0.05). Track C shows the trend in DAR as a connected scatterplot with each point in black representing the DAR value at a single nucleotide variant position (elastic sliding window size = 11 variants). Positions of the DE genes shown in track B are indicated by light red lines.