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Fig. 18 The long-term effect of N2 neutrophils on liver injury phenotype in ATP7B-KO mice. (A and B) Body weight and liver body ratio in wild-type and ATP7B-KO mice 4 months after STATTIC treatment. n = 6 mice/group. ?P < .05, ??P < .01, and ???P < .001. Serum activities of (C) ALT, (D) AST, (E) HDL-C, and (F) TChol in wild-type and ATP7B-KO mice 4 months after STATTIC treatment. n = 6 mice/group. ?P < .05, ???P < .001. (G) Pathologic changes in liver sections from wild-type and ATP7B-KO mice 4 months after STATTIC treatment. Left panel: Representative H&E images in paraffin-embedded liver sections. Scale bar: 50 ?m. Right panel: Representative images of Sirius red staining in paraffin-embedded liver sections. Scale bar: 100 ?m. WT, wild-type.