Fig. 1 Retina penetrating injury method and representative results. (A) Schematic of penetrating injury surgery procedure, and predicted injured site and regenerating RGCs with GFP expressed in gap43:GFP transgenic zebrafish. (B, C) Growth cones in regenerating RGCs marked by arrowheads. (D) Axonal varicosities (marked by arrowheads) in regenerating RGC axons. (E) Two-day postinjury retina flat-mount tiled image with magnified images of the injury site and the tip of regenerating RGC axons toward optic nerve head. Scale bars: (B, C) 10 μm; (D) 20 μm; (E) 200 μm. D, dorsal; GFP, green fluorescent protein; N, nasal; RGC, retinal ganglion cell; T, temporal; V, ventral.
Image
Figure Caption
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ J. Ocul. Pharmacol. Ther.