ZFIN Image: Kim et al., 2023, Figure 5

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Figure Caption

Figure 5

Inhibition of metastasis on A549 cells with MP06 in zebrafish embryos (A) Survival evolution through time of 48 h post fertilization (hpf) zebrafish embryos exposed to MP06 at different concentrations. (B) Quantification of metastatic rate of Tg(kdrl:GFP) zebrafish embryos microinjected with CM-DiI A549 cells at 5 dpi in zebrafish xenograft treated with MP06 (C) Injected A549 cells (red) immediately after xenograft (left) and at 5 dpi (right) (D) Xenografted zebrafish treated with 1, 2 μM MP06. Representative images show the invasive A549 cells (red) in the tail region of the embryos via vessels (green). (n = 30, ns: not statistically significant, Scale bars: 200 µm. * p < 0.01, ** p < 0.001).

Acknowledgments

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