ZFIN Image: Campbell et al., 2023, Fig. 6

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Figure Caption

Fig. 6 mrpl40 and prodha function independently from each other to regulate NSPC proliferation.

Number of Glast−/PH3+ (A) and Glast+/PH3+ (B) cells in mrpl40/prodha transheterozygotes and double mutants compared to single mutants. Double mutants have both prodha and mrpl40 single mutant phenotypes. Transheterozygotes display no phenotypes. Quantification one-way ANOVA, p-values are displayed on the plots. siblings (n = 20), transheterozygotes (n = 20), mrpl40 mutants (n = 10), prodha mutants (n = 10) and mrpl40;prodha double mutants (n = 9) from four biological replicates. PH3 staining in Tg(slc1a3b:H2AmCherry) line in wildtype (C), single prodha mutants (D), and double mutants (E). Double mutant has more severe hyperproliferative phenotype, revealing role for mrpl40 in Glast+ NSPCs.

Acknowledgments

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