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Fig. 7 Increased apoptosis in IDUA-deficient zebrafish larvae. TUNEL staining of cryopreserved tissue sections from control-MO, IDUA-MO, and IDUA-MO + WT-IDUA mRNA zebrafish larvae at 5 dpf. TUNEL-positive cells were detected in the eye, brain, and internal organs of IDUA-MO zebrafish larvae. Cell nuclei are stained with DAPI (blue). TUNEL image (first column), DAPI images (second column), and merged TUNEL/DAPI images (third column) are shown. All the images are representative of at least three independent experiments. Abbreviations: IDUA, α-l-iduronidase; MO, morpholino
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Full text @ Ann N Y Acad Sci