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Fig. 1 Schematic representation of D-BSA and DOX-loaded D-BSA NPs formations. DOX was loaded on D-BSA NPs containing tris-catechol-V(III) coordination at pH 7.4, and DOX was released in the acidic medium upon degradation of NPs via formation of mono-catechol-V(III) coordination. Injection of DOX-loaded D-BSA NPs to zebrafish larval vasculature killed circulating tumor cells.
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