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Fig. 9

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Publication: Santhanam et al., 2023 - Molecular basis of retinal remodeling in a zebrafish model of retinitis pigmentosa
All Figures: Figures for Santhanam et al., 2023

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Fig. 9

Comparative transcriptomic analysis of microglial/macrophage clusters and Müller glial cells in the zebrafish retina. A–C Microglia/Macrophages; D, E Müller glial cells. A Dot plot showing the specific enrichment of canonical markers cd74a and cd74b, as well as the non-canonical marker pfn1 in the microglia/macrophage cell clusters. B Violin plots showing the expression of cluster-specific markers between the two microglial/macrophage clusters (16 and 17). C Violin plot showing the expression of increased phagocytic and apoptotic markers in P23H microglia/macrophages. D Violin plots showing the specific enrichment of canonical Müller glial cell markers as well as changes in DEGs involved in mTOR signaling and amino acid catabolism. E Violin plots showing the decreased levels of DEGs involved in stem cell maintenance, lamellipodium assembly and sterol biosynthesis in P23H Müller glia

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