ZFIN Image: Santhanam et al., 2023, Fig. 8

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Figure Caption

Fig. 8

Comparative transcriptomic analysis of retinal ganglion cells in WT-P23H integrated dataset. A Dot plot showing the specific enrichment of canonical markers pou4f1, rbpms2a and rbpms2b in the RGC cluster compared to all other retinal cell types. rbpms2a and rbpms2b are present at lower levels in Müller glial cells (12) as well. B Dot plot showing the expression level and the percentage of cells expressing DEGs involved in different functional pathways between WT and P23H. C, D Violin plots showing increased levels of expression of DEGs involved in glutamate signaling (C), stress response and Wnt signaling (D) between WT and P23H RGCs

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