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Fig. 6 Optical control of RASopathy-induced heart defects. (A) Illustrations of examples of improper heart looping seen in zebrafish embryos. (B) Phenotypic analysis of embryo hearts at 48 hpf. N = number of embryos. NT = nontreated embryos. (C) Representative images of Tg(myl7:egfp) embryo hearts at 48 hpf. Pericardial edema is seen in the light-exposed embryos, suggesting impaired cardiac function. Scale bar = 200 μm.
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