ZFIN Image: Li et al., 2023, Figure 7

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Figure 7

Chlorahololide D inhibited proliferation and migration in vivo. CM-DiI stained MCF-7 cells were microinjected into 2 dpf zebrafish embryos. After 4 h, tumor-bearing embryos were treated with chlorahololide D (2.5, 5, and 10 μM) for 48 h (n = 15/group). Etoposide (10 μM) was used as the positive control. (A) Intensity and distribution of the red fluorescence were photographed using a confocal microscope of disseminated foci in zebrafish. (B) The proliferation was quantified by ImageJ software. (C) The metastasis of MCF-7 cells was analyzed using ImageJ software. All of the results are expressed as the mean ± SD. * p < 0.05 and *** p < 0.001 vs. the control group.

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