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Figure 3

ID: ZDB-IMAGE-231030-120
Publication: Huttner et al., 2023 - Loss of Sec-1 Family Domain-Containing 1 (scfd1) Causes Severe Cardiac Defects and Endoplasmic Reticulum Stress in Zebrafish
All Figures: Figures for Huttner et al., 2023

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Figure 3

Scfd1 deficiency leads to cardiac dysfunction in zebrafish embryos. Survival, heart rate, ventricular end-diastolic area (EDA) and fractional area change (FAC) are reduced in embryonic hah^vcc43−/− and scfd1^vcc44−/− mutants, while heterozygous siblings of both lines (+/−) are indistinguishable from wildtype (WT; +/+). Non-parametric survival test (Cox-Mantel) and two-way ANOVA p-values stated. Animal numbers, mean values, and multiple comparison p-values for all variables, time points, and genotypes listed in Supplementary Table S2; asterisk indicates significant differences from WT in hah^{vcc4 −/−} and scfd1^vcc44−/− mutants. Significance if p < 0.05. Created with BioRender.com.

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Phenotype details

Acknowledgments

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