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Figure 7
Remdesivir, Ritonavir, Molnupiravir, Baricitinib or Sabizabulin alter the inflammatory gene response in the absence of spike protein. qPCR results for inflammation associated gene expression in zebrafish larvae treaded with selected compounds. Remdesivir, Ritonavir, Molnupiravir, Baricitinib or Sabizabulin treatment is compared to larvae treated with DMSO. Bars represent mean and SD of 6 biological replicates. Each replicate consists of a pool of 5 larvae. Asterisks represent p-values from the Mann–Whitney U test * < 0.05; ** < 0.01;*** < 0.001. Note that in all graphs the same DMSO control samples were used.