ZFIN Image: Mahendra et al., 2023, Fig. 12

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Figure Caption

Fig. 12

Fig. 12. An overview of the anti-pigmentation potential of S. macrophylla. The potential pathways mediated by S. macrophylla seeds in decreasing zebrafish tyrosinase activity and therefore reducing the melanin formed in the embryos. Pure limonoids from the seed too may potentially be a good inhibitor against human TYRP-1, decreasing human pigmentation. (Coloured lines indicate the influence of each extract, fraction, or compound against pigment formation. Yellow: SMCE; grey: SMEAF; pink: SMHF; Blue: SMWF; red: limonoids. The dashed lines represent possible effect on skin pigmentation. The green arrows represent downregulation.) (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.).

Acknowledgments

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