Fig. 3 IAL inhibits CuSO4, tail-cutting, and LPS-induced inflammatory responses in zebrafish. (A) Changes of zebrafish immune cell migration in CuSO4-induced inflammatory model. The red arrows indicate inflammatory cells that migrated to the lateral line. (B) The number of inflammatory cells that migrated to the lateral line. (C) Changes of zebrafish immune cell migration in the tail cutting-induced inflammatory model. The red boxes indicate inflammatory cells that accumulate in the tail. (D) The IOD values of immune cells accumulated in the tail. (E) Changes of zebrafish immune cell migration in the LPS-induced inflammatory model. (F) The IOD values of zebrafish systemic immune cells. Data are expressed as mean ± SEM (n = 10). ####P < 0.0001 vs. the control group, ***P < 0.001, ****P < 0.0001 vs. the model group.
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