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Fig. 7
Antiangiogenesis activity of compound 1b in the transgenic zebrafish model. (A) Representative images of zebrafish embryos from transgenic zebrafish Tg (fli1:EGFP) treated with the vehicle and different concentrations of compound 1b (0.3, 1, and 3 μM) at 48 hpf. The absence and breakage of ISVs are indicated by red arrows. (B) Average total lengths of the ISVs of zebrafish after treatment with various concentrations of compound 1b. Results are presented as the means ± SD (n = 3). * p < 0.05, *** p < 0.001 vs. the control group.
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